Make Room in Your Heart & Home

Pet adoption, surrender support, and animal care services in Cape Girardeau—proudly serving Southeast Missouri families & their pets.

Meet Your New Best Friend

Looking to adopt a pet, surrender an animal, or get involved with your local shelter? We’re here to help. Located in Cape Girardeau, we provide caring adoption services, animal intake support, community education, and year-round programs for families and pet lovers throughout Southeast Missouri. Whether you're local or just passing through, you'll find our full-service shelter ready to serve people & pets alike.

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A brown and white dog is standing on a leash in the dirt and looking at the camera.

Surrender

Life happens. If you’re facing a tough situation and need to give up a pet, we’re here with no judgment. Our team will walk you through the surrender process and help make sure your animal is cared for and has the best chance at a new life.

A brown and white dog is sticking its tongue out in the grass.

Adoption

We’re here to help you find the perfect match. Every day, we care for dogs, cats, puppies & kittens who are waiting for a second chance. Some are energetic and playful, others are calm and cuddly—but all of them are ready to be loved. Our adoption listings are updated daily so you can browse available pets and meet them in person when you’re ready.


Every adopted animal comes fully vaccinated, spayed or neutered, microchipped, and ready to become part of your family. Whether you’re a first-time pet owner or a lifelong animal lover, we’ll guide you through the process and help you find a companion who fits your lifestyle.

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Services

We offer compassionate pet cremation services right on-site. For Southeast Missouri residents in need of affordable veterinary care, our SNAP program provides access to low-cost spay & neuter support. Need a venue for a birthday or baby shower? Our community room is available for local rentals.

Support Our Work

Donate or Volunteer Today

We rely on donations and volunteers from across Cape County and beyond. Whether you give through PayPal, Venmo, or donate your time at the shelter, your support makes a direct impact. Every dollar helps us rescue, rehabilitate & rehome animals throughout Southeast Missouri.

We Are a No-Kill Shelter!

Every animal that comes through our doors is safe. We’re committed to giving every pet the time, care & chance they deserve—no matter how long it takes.

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Contact us to learn more about eligibility, how to apply, or which clinics participate in the SNAP program.

Have Questions About SNAP?

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Full-Service Animal Shelter:

We provide adoption, intake, cremation, and community services all under one roof.

Locally Rooted:

Based in Southeast MO, we support families & pets from around the area & nearby towns.

Mission-Driven Team:

Our staff & volunteers work every day to give animals a second chance at life.

Community-Funded:

As a nonprofit, we rely on donations, sponsorships & grassroots support—not government funding.

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A woman is kneeling down next to a dog on a leash.
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Our Mission

Southeast Missouri Pets serves our communities by nurturing the human pet bond by providing shelter care and advocacy for homeless pets and providing spay and neuter resources and education for people.

Our Facility

The All-New Adoption & Humane Education Center

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A building with a sign that says squirrel rescue

Our updated center was built to meet and exceed Missouri Department of Agriculture regulations, offering a safer, more comfortable space for animals and visitors alike. Here's what you'll find inside:

  • Modern Ventilation Systems
    Each area is equipped with separate air systems to reduce the spread of illness.
  • Durable, Easy-to-Clean Surfaces
    Every room was designed for proper sanitation and long-term health.
  • Spacious Dog Kennels
    Larger enclosures with built-in drainage help keep dogs warm, dry & comfortable.
  • Cat-Friendly Group Housing
    Cats enjoy open rooms with space to move, climb & interact in a low-stress environment.
  • Expanded Humane Education Space
    We now offer classrooms for camps, school visits & programs that promote empathy and kindness.

Call us at 573.334.5837, stop by during open hours, or send us a message through our contact page. Come visit and see how you can make a difference.

Whether you're looking to adopt, surrender, volunteer, or just have a question—our team is here to help.

A black paw print on a white background.