Our Mission

About Semopets

We are a no kill pet center which allows us to better serve our communities by nurturing the human-pet bond by providing shelter care and advocacy for homeless pets and providing spay and neuter resources and education for people.

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Available Pets

Southeast Missouri Pets has hundreds of adoptable animals in our care.

Find your best friend today!

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The All New

Adoption & Humane Education Center

The new center meets and exceeds regulations from the State of Missouri Department of Agriculture and offers:

  • Improved lives of people and pets.

  • Separate ventilation systems to help control spread of disease.

  • Proper surfaces that can be maintained and cleaned.

  • Group housing for cats allowing for interaction and space.

  • Larger kennels with systems in place to prevent disease.

  • Proper drainage to keep the pets warm and dry.

  • Larger spaces reducing stress for pets.

  • The new building will allow us to expand our services.

  • Humane education programs that will encourage empathy and compassion in years to come.

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Come Visit Us

Hours of Operation


10:00 am – 5:00 pm


10:00 am – 5:00 pm

Closed Tuesdays

180 Weston Street Cape Girardeau, MO 63701

Important note

Appointments are recommended but not required. The last adoption appointment of the day is 30 minutes prior to close. The adoption process takes about 30 minutes to complete.

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Join the journey to unleash the future

Adopt Today